Aims and Fit of Module

This module aims to provide students with fundamental knowledge in pharmacology, and particularly from a qualitative and quantitative standpoint, all the processes and factors affecting a drug in order to optimize its bioavailability. It will equip students with the basic pharmacokinetics and pharmacodynamics (PKPD) principles and concepts, as well as a thorough knowledge about mathematical models and statistical analyses related to PKPD.

Learning outcomes

A Understand the common terms and fundamentals of pharmacology
B Evaluate potential druggable candidates’ pharmacokinetics and pharmacodynamics (PKPD) properties
C Demonstrate an understanding of the process about the drug’s absorption, distribution, metabolism and excretion (ADME) pattern.
D Demonstrate an understanding of the interrelationship of the physicochemical properties of a drug in dosage form and the pharmacology, toxicology and clinical response after administration.
E Demonstrate an understanding of the time relation of drug action both mathematically and descriptively.
F Apply PKPD models to predict the evolution of the drug in the body and to establish appropriate dosing regimens.

Method of teaching and learning

This course will be taught by a series of lectures. Students will learn how to apply their knowledge by completing a series of related tutorials.