Module Catalogues, Xi'an Jiaotong-Liverpool University   
 
Module Code: BIO206
Module Title: Practical Bioinformatics
Module Level: Level 2
Module Credits: 5.00
Academic Year: 2019/20
Semester: SEM2
Originating Department: Biological Sciences
Pre-requisites: N/A
   
Aims
The new module is designed for biology majors, with a heavy emphasis on the steps required to perform bioinformatics analysis to answer biological questions. The aim of this module is mainly to prepare our students with necessary conceptual and practical background in bioinformatics, help our students to realize the power of computational approaches and get familiar with statistics/modeling/algorithms in biology research.
Learning outcomes 
On successful completion of this module, students will be able to:

A. Demonstrate a systematic knowledge and understanding of the application of informatics in life sciences

B. Demonstrate information literacy skills in the discovery, evaluation and acquisition of data.

C. Analyse datasets of broad biological relevance, using tasks and workflows that will prepare them for future research projects.

D. Use local and web-based tools to conduct essential bioinformatics tasks, as required in research.

E. Report their research findings in appropriate format.


Method of teaching and learning 
The course will be conducted as lectures and hands-on practice. Bioinformatics algorithms are conceptually delivered but not required. The students will use open source software tools to work with public datasets to solve various practical bioinformatics problems; and then prepare formal reports to present their findings.
Syllabus 
Specifically, the following contents will be covered

1 Genomics, Bioinformatics & Molecular Biology

2 Systematic Literature Search

3 Human Genome Project

4 Genome and Sequence Databases

5 Protein Sequence and Motif Databases

6 Sequence Alignment

7 Sequence Similarity Search

8 Multiple Sequence Alignment

9 Distance based Phylogenies

10 Building Protein Motifs and Models

11 Ab initio Protein Structure Prediction

12 Clustering Coordinately Regulated Genes

13 Discovering Gene Regulatory Signals

14 Gene Regulatory Modules and Networks

15 MicroRNA Regulatory Networks, Protein-Protein interaction network

16 Simple Nucleotide Polymorphisms (SNPs)

17 Genome Variations

18 Genome-Wide Association Studies

19 Gene expression and Gene Ontology analysis

20 Metabolic Pathways and Analyses



Delivery Hours  
Lectures Seminars Tutorials Lab/Prcaticals Fieldwork / Placement Other(Private study) Total
Hours/Semester 39   2  11  50    50  150 

Assessment

Sequence Method % of Final Mark
1 Practical Report 1 10.00
2 Practical Report 2 15.00
3 Practical Report 3 15.00
4 Practical Report 4 20.00
5 Final Project 40.00

Module Catalogue generated from SITS CUT-OFF: 5/23/2019 5:40:23 AM