Module Catalogues, Xi'an Jiaotong-Liverpool University   
Module Code: BIO305
Module Title: Gene Expression and Genome Analysis
Module Level: Level 3
Module Credits: 5.00
Academic Year: 2020/21
Semester: SEM1
Originating Department: Biological Sciences
Pre-requisites: N/A
This module is for Level 3 undergraduates in Biological Sciences and aims for students to understand how gene expression of eukaryotes is regulated with the different mechanisms, for example, in response to the changes of environment. It will explain how eukaryotes control the gene expression at the different steps in a
regulatory network by focusing on both model and non-model organisms. In addition, it will introduce the current techniques used for a large scale analysis of whole genome to open up a new era of Molecular Biology.
It will also provide an opportunity to use and apply these techniques to examine the several specific features of genomic DNA as well as protein sequences.
Learning outcomes 
On successful completion of this module, students should be able to demonstrate an advanced knowledge and understanding of gene expression and genome analysis in the following areas:

A. Understand how gene expression in eukaryotes is regulated.

B. Comprehend how and why both model a305nd non-model organisms have been used for research on gene expression and genome analysis.

C. Understand thoroughly the recent techniques to analyze genes at whole genome level.

D. Critically evaluate the results of basic genome analysis using various databases and tools available in NCBI.

E. Critically read and evaluate the recent literatures on gene expression and genome analysis.

Method of teaching and learning 
Module content will be delivered by a combination of lectures and workshops. The contents of lectures (power point files) are also available on Web. For workshops, each student will need a lap top computer with internet connection.
Lecture 1, 2

Mechanism of gene transcription initiation in eukaryotic cells

Lecture 3, 4

Chromatin structures

Lecture 5, 6

Transcriptional regulation of gene expression

Lecture 7, 8

Techniques to analyze gene expression

Lecture 9, 10

Post-transcriptional regulation of gene expression I (mRNA processing)

Lecture 11, 12

Post-transcriptional regulation of gene expression II (Non-coding RNAs, RNA interference)

Lecture 13, 14

Post-transcriptional regulation of gene expression III (translation)

Lecture 15, 16

Changes of DNA structure in genome

Lecture 17, 18

Epigenetic regulation of gene expression

Lecture 19, 20

Molecular mechanisms underlying animal behavior and emotion

Lecture 21, 22

Molecular mechanisms underlying animal diversity

Lecture 23, 24

Introduction to Genomes

Lecture 25, 26

Techniques to analyze genes at whole genome level

Lecture 27, 28

Comparative genomics
Delivery Hours  
Lectures Seminars Tutorials Lab/Prcaticals Fieldwork / Placement Other(Private study) Total
Hours/Semester 28    14      108  150 


Sequence Method % of Final Mark
1 Continuous Assessment 15.00
2 Final Exam 85.00

Module Catalogue generated from SITS CUT-OFF: 6/7/2020 4:49:03 AM