Module Catalogues, Xi'an Jiaotong-Liverpool University   
 
Module Code: CHE215
Module Title: Analytical Chemistry
Module Level: Level 2
Module Credits: 5.00
Academic Year: 2020/21
Semester: SEM1
Originating Department: Chemistry
Pre-requisites: N/A
   
Aims
This course covers the theory and application of common separation techniques in use in chemistry. The main focus is however, on chromatographic techniques.
Learning outcomes 
A explain the terminology used in separation sciences

B describe the general methods used for separation of mixtures and select the most appropriate one in industry and research settings

C discuss the principles governing the separation of molecules and ions in chromatography and explain plate number and separation power of a column

D discuss the key configuration of HPLC and GC

E discuss the application of these separation techniques in industries and research settings

F Select and use the most appropriate separation technique for an unknown mixture

G Optimize chromatographic separation
Method of teaching and learning 
Lectures, tutorials and laboratory sessions
Syllabus 
• Methods for the Separation of mixtures

o solvent-solvent extraction

o distillation

o chromatography

o centrifugation

o electrophoresis

• Solvents

o polarity, viscosity, miscibility, UV cutoff, solvent strength, mixing solvents

• Sample preparation and precision of measurement

o cleaning of samples

o errors in measurements

• Introduction to chromatography

o general description

o fundamental principles and equations describing separation

o band broadening

o column efficiency

• General performance characteristics of chromatography

o linearity

o sensitivity

o optimization of column performance

o quantification

• Derivatization in chromatographic analysis

o modification of column materials

• Column chromatography, Thin layer , Size exclusion, Chiral chromatography

• HPLC


o Introduction

o Instrumentation: Pumps, injector, mobile phase handling, detector

o Normal phase, reverse phase

o Ion chromatography

o Measurement of caffeine in soft drinks using HPLC

• Gas chromatography

o Introduction

o Mobile and stationery phases

o Columns

o Detection

o Identification of volatile organic compounds by GC-MS

• Introduction to Electrophoresis


Ø Lab practicals to support the teaching theory in the following areas:

• Extraction (liquid-liquid, liquid-solid)

• Fractional distillation

• centrifugation

• Different techniques of GC/HPLC

• Optimization of HPLC analysis

• Electrophoresis

Delivery Hours  
Lectures Seminars Tutorials Lab/Prcaticals Fieldwork / Placement Other(Private study) Total
Hours/Semester 26    13  40    71  150 

Assessment

Sequence Method % of Final Mark
1 Final Exam 60.00
2 Laboratory Work Cw 40.00

Module Catalogue generated from SITS CUT-OFF: 6/3/2020 1:31:09 AM